Changes Relative to Baseline in Entire Sample with Calibration of PET Scores to ADAS-cog Scale, Signal Strength, and Relative Required Sample Sizes in Clinical Trials

VariableMeanSDVarianceCohen dSample size*
Change at 6 m
Change at 12 m
Change at 24 m
  • * Relative to 12-mo study using ADAS-cog (set to n = 100).