TABLE 1

Biodistribution of ^99mTc[P(VLA-co-VNI)](tricine)₂ in Normal Mice

	Control (min)			Block with P(VLA-co-VNI) (min)			Block with neogalactosylalbumin (min)
	10	30	120	10	30	120	10	30	120
Heart	0.71 ± 0.13	0.71 ± 0.18	0.62 ± 0.17	6.69 ± 2.11	0.62 ± 0.31	0.65 ± 0.19	3.19 ± 0.59	1.11 ± 0.41	1.10 ± 0.25
Liver	125.33 ± 10.99	122.64 ± 9.06	114.74 ± 9.93	34.12 ± 3.24	67.81 ± 5.28	63.33 ± 5.21	58.05 ± 5.27	75.30 ± 4.99	56.45 ± 8.53
Lung	0.88 ± 0.24	0.76 ± 0.24	0.42 ± 0.18	14.79 ± 5.22	0.87 ± 0.19	0.70 ± 0.27	9.19 ± 1.04	0.83 ± 0.20	0.96 ± 0.36
Kidney	2.42 ± 0.35	2.92 ± 0.82	2.40 ± 0.66	14.70 ± 3.48	5.33 ± 0.57	4.50 ± 0.73	10.28 ± 1.15	4.50 ± 0.74	5.08 ± 0.62
Spleen	1.92 ± 0.91	2.53 ± 1.13	1.35 ± 0.71	4.49 ± 1.23	0.61 ± 0.08	0.54 ± 0.12	6.71 ± 1.40	6.56 ± 1.55	6.89 ± 2.47
Stomach	0.51 ± 0.24	0.88 ± 0.24	0.52 ± 0.23	0.30 ± 0.08	0.22 ± 0.06	0.77 ± 0.46	0.23 ± 0.13	0.25 ± 0.14	0.32 ± 0.12
Blood	0.23 ± 0.07	0.07 ± 0.01	0.02 ± 0.01	30.48 ± 7.18	0.15 ± 0.03	0.04 ± 0.00	16.55 ± 2.60	0.16 ± 0.07	0.03 ± 0.00
Bone	1.02 ± 0.28	0.98 ± 0.18	0.86 ± 0.31	4.74 ± 1.00	0.91 ± 0.13	1.02 ± 0.41	3.50 ± 0.62	1.73 ± 0.46	2.37 ± 0.74
Muscle	0.38 ± 0.08	0.51 ± 0.27	0.43 ± 0.11	1.28 ± 0.50	0.54 ± 0.17	0.39 ± 0.11	0.81 ± 0.18	0.47 ± 0.23	0.55 ± 0.30
Small intestine	0.85 ± 0.30	2.93 ± 2.49	1.46 ± 0.35	1.79 ± 0.37	1.93 ± 0.21	0.88 ± 0.28	1.38 ± 0.08	1.92 ± 0.72	1.03 ± 0.27

Data are biodistribution 10, 30, and 120 min after intravenous injection of ^99mTc[P(VLA-co-VNI)](tricine)₂ into normal mice, and results of blocking experiment with preinjection of free neogalactosylalbumin or P(VLA-co-VNI) as inhibitor. Data are expressed as mean %ID/g ± SD (n = 5).