Toxicity and Response
| Toxicity | 12th wk | ||||||
| Patient no. | Histology | Absolute neutrophil count < 500/mm3 (grade IV) | Platelet count < 25,000/mm3 (grade IV) | Blood product support | WBC count (/mm3) | Platelet count (/mm3) | Response |
| 1 | DLBCL | No | No | No | 6,300 | 251,000 | CR |
| 2 | DLBCL | No | No | No | 4,400 | 78,000 | CR |
| 3 | Follicular lymphoma | No | Yes | Yes | 3,700 | 243,000 | SD |
| 4 | DLBCL | No | Yes | Yes | 2,100 | 124,000 | CR |
| 5 | Follicular lymphoma | No | No | No | 7,500 | 118,000 | PD |
| 6 | DLBCL | Yes | Yes | Yes | 1,900 | 231,000 | CR |
| 7 | DLBCL | No | No | No | 3,400 | 86,000 | CR |
WBC = white blood cell; CR = complete response; SD = stable disease; PD = progressive disease.