TABLE 3

Concerns About Treatment of NHL Patients with 90Y-Ibritumomab Tiuxetan or 131I-Tositumomab Grouped by Positive (≥4) or Negative (<4) Predicted Future

Mean rating
ConcernPositive future (≥4)Negative future (<4)P
90Y-Ibritumomab tiuxetan administration is too complicated in general*1.622.060.02
We have concerns about the radiation safety*1.692.19<0.01
We have concerns about the dosimetry procedure*1.822.33< 0.01
131I-tositumomab or 90Y-ibritumomab tiuxetan take too much time from my practice in general*1.942.39< 0.01
Most nuclear physicians are not trained to administer potentially myeloablative therapies such as 90Y-ibritumomab tiuxetan or 131I-tositumomab*2.272.87< 0.01
There might be unexpected late side effects of 131I-tositumomab or 90Y-ibritumomab tiuxetan treatment (myelodysplastic syndrome)2.302.440.45
Concerns exist that subsequent treatments will not be possible after 131I-tositumomab or 90Y-ibritumomab tiuxetan administration2.412.600.33
90Y-ibritumomab tiuxetan or 131I-tositumomab therapy provides poor payment for the time and effort in the radiolabeling process2.422.640.17
131I-tositumomab or 90Y-ibritumomab tiuxetan treatment does not have enough reported randomized studies2.492.520.74
131I-tositumomab administration is too complicated in general*2.562.350.01
90Y-ibritumomab tiuxetan or 131I-tositumomab therapy provides poor payment for the time and effort in the administration process2.942.900.3
Oncologists and hematologists prefer to treat by themselves with nonradioactive compounds3.483.380.2
131I-tositumomab or 90Y-ibritumomab tiuxetan treatment is too expensive3.513.270.18
  • * Considered significant difference.

  • P < 0.05 was considered significant.