TABLE 2

Comparison of 18F-FDG Uptake and Biomarkers Between Malignant Lesions and Benign Lesions

Pulmonary metastasis vs. control groupPrimary lung cancer vs. control group
BiomarkerMalignant (n = 146)Benign (n = 29)PMalignant (n = 140)Benign (n = 29)P
T/M ratio3.25 ± 0.222.12 ± 0.250.02615.96 ± 0.382.12 ± 0.25<0.0001
Glut12.92 ± 0.081.83 ± 0.16<0.00012.42 ± 0.091.83 ± 0.160.0048
Glut31.27 ± 0.051.76 ± 0.150.00031.30 ± 0.061.76 ± 0.150.0012
Hexokinase I2.53 ± 0.091.89 ± 0.150.00222.81 ± 0.101.89 ± 0.15<0.0001
HIF-1α2.90 ± 0.092.10 ± 0.170.00033.42 ± 0.112.10 ± 0.17<0.0001
VEGF23.9 ± 1.5013.2 ± 2.340.002430.3 ± 1.7013.2 ± 2.34<0.0001
CD3425.1 ± 0.9017.8 ± 1.730.001924.0 ± 1.1017.8 ± 1.730.0125