TABLE 1

Comparison of 18F-FDG Uptake and Biomarkers Between Pulmonary Metastases and Primary Lung Cancer

All casesAdenocarcinomaSQC
BiomarkerMetastasis (n = 146)Primary (n = 138)PMetastasis (n = 103)Primary (n = 93)PMetastasis (n = 13)Primary (n = 45)P
T/M ratio3.25 ± 0.225.96 ± 0.38<0.00013.42 ± 0.274.47 ± 0.400.02813.67 ± 0.789.04 ± 0.64<0.0001
Glut12.92 ± 0.082.42 ± 0.09<0.00013.12 ± 0.092.02 ± 0.09<0.00013.39 ± 0.183.23 ± 0.090.4716
Glut31.27 ± 0.051.30 ± 0.060.62501.12 ± 0.041.29 ± 0.070.02201.46 ± 0.221.33 ± 0.100.5616
Hexokinase I2.53 ± 0.092.81 ± 0.100.02952.55 ± 0.092.49 ± 0.120.69793.15 ± 0.323.45 ± 0.130.3244
HIF-1α2.90 ± 0.093.42 ± 0.110.00043.02 ± 0.102.50 ± 0.120.00073.69 ± 0.174.15 ± 0.150.1246
VEGF23.9 ± 1.5030.3 ± 1.700.005024.0 ± 1.7024.5 ± 1.800.838141.5 ± 5.1044.9 ± 2.700.5615
CD3425.1 ± 0.9024.0 ± 1.100.451824.4 ± 1.1020.3 ± 1.300.016032.9 ± 2.5031.5 ± 1.300.6115