TABLE 2

Single-Photon Techniques for Early Detection of Cardiotoxicity

TechniqueTracer
Mechanical (pump) function99mTc MUGA (radionuclide ventriculography or equilibrium radionuclide angiocardiography)
99mTc gated blood-pool SPECT
Neuronal imaging123I-MIBG
See Table 3 for neuronal imaging PET tracers
Imaging necrosis/cell death111In-antimyosin
Imaging cell death/apoptosis99mTc-annexin V
Fatty acid use123I-BMIPP
123I-paraphenyl pentadecanoic acid
Therapeutic target imaging111In-trastuzumab