TABLE 1

Biodistribution of 64Cu-SarAr-SA-Aoc-Bombesin(7-14) and 64Cu-SarAr-SA-Aoc-GSG-Bombesin(7-14) in Mice Bearing PC-3 Tumors (% ID/g ± SEM; n = 5) at 1, 4, and 24 Hours

64Cu-SarAr-SA-Aoc-bombesin(7-14)64Cu-SarAr-SA-Aoc-GSG-bombesin(7-14)
Tissue1 h4 h24 h1 h4 h24 h
Blood0.936 ± 0.1650.181 ± 0.0310.072 ± 0.0090.769 ± 0.0320.080 ± 0.0070.024 ± 0.005
Lung1.246 ± 0.1060.679 ± 0.0280.367 ± 0.0261.241 ± 0.0620.348 ± 0.0170.216 ± 0.014
Liver9.467 ± 1.4358.263 ± 0.4524.681 ± 0.2895.061 ± 0.2852.959 ± 0.1382.824 ± 0.274
Spleen1.233 ± 0.1863.185 ± 1.2100.970 ± 0.1841.507 ± 0.0631.073 ± 0.0660.931 ± 0.091
Kidney9.367 ± 0.8988.303 ± 0.5585.159 ± 0.2847.076 ± 0.2685.532 ± 0.4594.731 ± 0.198
Muscle0.923 ± 0.2740.272 ± 0.0770.095 ± 0.0170.392 ± 0.0220.093 ± 0.0030.074 ± 0.008
Bone1.740 ± 0.5250.815 ± 0.0350.469 ± 0.0251.411 ± 0.3350.533 ± 0.0220.498 ± 0.040
Pancreas67.392 ± 4.57348.422 ± 5.25036.935 ± 3.77052.036 ± 4.42329.540 ± 1.15829.888 ± 1.599
Tumor13.015 ± 0.93210.805 ± 1.0917.365 ± 0.9118.541 ± 0.8064.913 ± 0.5713.937 ± 0.322