TABLE 3

Results of Liver Function Tests

Test	Day 0	Day 1	Day 3	Day 5	Day 7
GEC	100% ± 15.0%	113.9% ± 22.7%	118.9% ± 22.1%	135.0% ± 19.1% ^*	123.7% ± 17.2% ^*
ICG	100% ± 14.1%	56.5% ± 18.6% ^*	86.4% ± 15.0%	87.3% ± 21.1%	95.2% ± 15.4%
^99mTc-mebrofenin uptake	100% ± 7.3%	68.7% ± 14.1% ^*	91.1% ± 13.97%	103.9% ± 15.8%	106.2% ± 16.3%
^99mTc-mebrofenin excretion	100% ± 13.4%	78.8% ± 5.9%	100.2% ± 49.9%	166.6% ± 22.2% ^*	152.1% ± 45.1% ^*
^99mTc-GSA uptake	100% ± 16.8%	77.0% ± 19.3%	66.9% ± 14.5% ^*	72.1% ± 15.8% ^*	83.1% ± 15.1%

↵* Statistically significant differences from baseline levels.
For intrinsic regulation of liver function, data derived from quantitative liver function test were divided by total liver (wet) weight and subsequently expressed as mean ± SD percentage of control.