TABLE 2

Parameter Estimates of Reversible 1-Tissue-Compartment Model for Asymptomatic Patients

RegionIFK1 (mLplasma· min−1· mLextravascular tissue−1)k2 (min−1)Blood volumeVT (mLplasma· mLextravascular tissue−1)Residual sum of square errors
Bone marrowTotal-plasma BSIF0.111 ± 0.0490.043 ± 0.0130.196 ± 0.1292.479 ± 0.5133.569 ± 3.982
Parent-plasma BSIF0.151 ± 0.0720.024 ± 0.0100.171 ± 0.1236.036 ± 0.7493.911 ± 3.937
Total-plasma IDIF0.088 ± 0.0340.039 ± 0.0080.036 ± 0.0552.510 ± 0.5453.000 ± 2.925
Parent-plasma IDIF0.108 ± 0.0450.017 ± 0.0060.027 ± 0.0586.017 ± 0.9294.002 ± 2.583
Lung parenchymaTotal-plasma BSIF−5.153 ± 10.313*2.541 ± 4.8291.292 ± 1.574*−0.496 ± 1.075*6.734 ± 5.159
Parent-plasma BSIF−0.173 ± 0.356*0.379 ± 0.5950.675 ± 0.342−0.074 ± 0.329*7.322 ± 5.364
Total-plasma IDIF0.036 ± 0.0080.205 ± 0.0660.280 ± 0.1120.187 ± 0.0423.225 ± 3.375
Parent-plasma IDIF0.034 ± 0.0050.120 ± 0.0460.287 ± 0.1140.313 ± 0.1213.607 ± 3.747
Mean of aortic walls (descending, arch, ascending)Total-plasma BSIF−3.805 ± 5.076*2.222 ± 2.1301.839 ± 1.465*−0.710 ± 1.123*22.412 ± 22.544
Parent-plasma BSIF−0.445 ± 0.579*0.577 ± 0.5131.016 ± 0.522*−0.133 ± 0.958*30.433 ± 21.391
Total-plasma IDIF0.014 ± 0.0080.050 ± 0.0230.449 ± 0.1210.275 ± 0.1196.863 ± 5.327
Parent-plasma IDIF0.016 ± 0.0090.030 ± 0.0120.449 ± 0.1200.580 ± 0.2486.829 ± 5.269
  • * Blood volume (bv) > 1, K negative, VT negative.

  • Data are mean ± SD (n = 4). For all regions considered, kinetic parameters were computed for 4 BSIFs and IDIFs.