TABLE 3

Comparison of Radioligands for Imaging Human SSTr Reporter Gene

		Uptake
Transduced xenograft	Ligand	% dose/cm³	Ratio of transduced to WT	Ratio of transduced to muscle	References
SKOV3	¹¹¹In-DTPA-octreotide	32 (4 h)^*^†	38 (4 h)^*^†	30 (4 h)	Rogers et al. (14)
A-427	^99mTc-P829	2.5 (5 h)^*^†	4 (3 h)^*^†	4 (3 h)	Zinn et al. (16)
	¹⁸⁸Re-P829	2.2 (5 h)^*^†
SKOV3	^99mTc-P2045	4.0 (2 h)^*^†	12.2 (5 h)^*^†	ND	Chaudhuri et al. (38)
A-427	^94mTc-demotate 1		>5 (2 h)^*^‡	10 (1 h), 20(2 h)	Rogers et al. (17)
HT1080	¹¹¹In-DTPA-octreotide	1.7 (24 h)^*^†	14 (24 h)^*^†	42 (24 h)	Yang et al. (39)
MDA-MB-435	¹¹¹In-DTPA-octreotide	1.8 (24 h)^*^†	18 (24 h) ^*^†	27 (24 h)	Singh et al. (40)
C6	⁶⁸Ga-DOTATOC	15 (2 h)^*^‡	64 (2 h)^*^‡	∼500 (2 h)	Current work