Baseline Characteristics of Study Subjects Stratified by hsCRP and LDL-C Levels
| hsCRP | |||||
| <2 mg/L | ≥2 mg/L | ||||
| Characteristic | LDL-C < 130 mg/dL (n = 30) | LDL-C ≥ 130 mg/dL (n = 30) | LDL-C < 130 mg/dL (n = 30) | LDL-C ≥ 130 mg/dL (n = 30) | P |
| Male (n) | 16 (53.3) | 18 (60.0) | 14 (46.7) | 22 (73.3) | 0.19 |
| Age (y) | 52.5 ± 8.3 | 49.7 ± 8.3 | 47.2 ± 12.3 | 51.2 ± 10.2 | 0.19 |
| BMI (kg/m2) | 22.2 ± 2.6* | 24.3 ± 2.4† | 25.4 ± 3.9† | 26.0 ± 3.1† | <0.01 |
| Waist circumference (cm) | 78.7 ± 7.6* | 84.1 ± 7.3† | 86.0 ± 7.9† | 89.1 ± 6.4† | <0.01 |
| Systolic blood pressure (mm Hg) | 121.4 ± 14.6 | 121.4 ± 13.3 | 125.0 ± 13.8 | 129.5 ± 28.4 | 0.29 |
| Diastolic blood pressure (mm Hg) | 78.8 ± 7.8* | 81.0 ± 9.7* | 82.9 ± 11.5* | 89.8 ± 11.1† | <0.01 |
| LDL-C (mg/dL) | 79.9 ± 19.5* | 162.6 ± 19.7† | 107.2 ± 16.3‡ | 156.2 ± 23.4† | <0.01 |
| HDL-C (mg/dL) | 47.1 ± 15.9 | 52.1 ± 11.8 | 46.8 ± 12.9 | 44.8 ± 9.4 | 0.15 |
| Triglycerides (mg/dL) | 57.0 (46.0–82.3)* | 102.0 (72.8–148.8)† | 109.5 (80.8–213.8)†,‡ | 142.0 (112.3–190.8)‡ | <0.01 |
| Fasting blood glucose (mg/dL) | 72.9 ± 11.2* | 92.0 ± 10.2† | 95.5 ± 13.2† | 98.9 ± 10.2† | <0.01 |
| hsCRP (mg/L) | 0.29 (0.20–0.56)* | 0.52 (0.41, 0.73)† | 3.13 (2.41, 6.91)‡ | 3.29 (2.50, 5.61)‡ | <0.01 |
| Current smoker (n) | 6 (20.0) | 11 (36.7) | 7 (24.1) | 9 (30.0) | 0.50 |
↵*,†,‡ No statistical difference between 2 groups, based on Tukey's HSD post hoc analysis.
Data are expressed as mean ± SD; median, with interquartile range in parentheses; or number, with percentage in parentheses. P value for overall difference among groups was calculated from ANOVA, Kruskal–Wallis H test, or Pearson χ2 test.