TABLE 1.

Distribution in Mice

Ligand	Tissue	1 min	5 min	15 min	30 min	60 min	90 min
¹⁸F-FEAC	Blood	1.84 ± 0.38	0.85 ± 0.02	0.66 ± 0.00	0.67 ± 0.04	0.82 ± 0.17	0.73 ± 0.06
	Heart	15.55 ± 1.42	9.59 ± 1.17	5.45 ± 0.14	3.51 ± 0.10	2.40 ± 0.20	2.09 ± 0.04
	Lung	82.68 ± 14.71	35.27 ± 3.50	23.57 ± 2.52	16.47 ± 2.21	10.38 ± 1.23	8.18 ± 0.42
	Liver	4.88 ± 0.92	9.28 ± 1.83	9.72 ± 0.58	7.12 ± 0.57	5.36 ± 0.31	4.60 ± 0.45
	Spleen	2.32 ± 0.15	7.80 ± 1.13	8.83 ± 0.70	7.43 ± 0.72	5.35 ± 0.68	5.25 ± 0.16
	Kidney	14.94 ± 1.56	17.09 ± 4.01	15.64 ± 0.55	11.96 ± 0.76	8.65 ± 0.66	7.48 ± 0.52
	Small intestine	4.33 ± 0.59	5.44 ± 1.10	7.99 ± 1.04	13.96 ± 3.19	7.53 ± 1.52	7.08 ± 3.49
	Testicle	0.46 ± 0.03	0.53 ± 0.10	0.69 ± 0.01	0.72 ± 0.05	0.80 ± 0.05	0.84 ± 0.02
	Muscle	2.16 ± 0.75	1.80 ± 0.31	1.66 ± 0.26	1.34 ± 0.15	1.30 ± 0.11	1.10 ± 0.07
	Bone	1.05 ± 0.45	1.35 ± 0.20	1.41 ± 0.17	1.21 ± 0.18	1.65 ± 0.19	1.40 ± 0.45
	Brain	1.06 ± 0.09	0.69 ± 0.08	0.45 ± 0.05	0.40 ± 0.02	0.42 ± 0.02	0.45 ± 0.03
¹⁸F-FEDAC	Blood	1.77 ± 0.16	0.82 ± 0.21	0.74 ± 0.14	0.72 ± 0.09	0.66 ± 0.02	0.45 ± 0.09
	Heart	15.29 ± 2.09	8.32 ± 0.80	5.71 ± 0.66	3.78 ± 0.31	2.40 ± 0.10	1.38 ± 0.17
	Lung	61.75 ± 4.49	27.75 ± 6.88	23.28 ± 4.17	16.77 ± 0.78	10.30 ± 0.54	6.59 ± 0.87
	Liver	7.65 ± 1.98	10.29 ± 1.00	10.51 ± 1.29	10.36 ± 0.72	7.09 ± 0.46	4.65 ± 0.33
	Spleen	3.49 ± 1.41	5.57 ± 0.97	7.14 ± 0.94	7.43 ± 0.49	5.77 ± 0.39	3.86 ± 0.67
	Kidney	17.75 ± 3.17	15.49 ± 0.83	14.11 ± 1.46	14.40 ± 0.80	9.08 ± 0.45	5.63 ± 1.07
	Small intestine	5.84 ± 1.20	5.62 ± 0.11	7.14 ± 0.80	14.05 ± 7.43	9.57 ± 2.12	6.98 ± 3.15
	Testicle	0.51 ± 0.06	0.61 ± 0.14	0.72 ± 0.10	0.92 ± 0.14	0.81 ± 0.14	0.54 ± 0.16
	Muscle	2.38 ± 0.13	1.96 ± 0.32	2.01 ± 0.47	1.66 ± 0.21	1.27 ± 0.28	0.64 ± 0.21
	Bone	1.85 ± 0.88	1.78 ± 0.35	1.84 ± 0.44	2.18 ± 0.33	2.02 ± 0.44	1.33 ± 0.13
	Brain	1.00 ± 0.14	0.67 ± 0.10	0.45 ± 0.03	0.40 ± 0.04	0.33 ± 0.03	0.21 ± 0.05

Data are %ID/g tissue (mean ± SD; n = 3).