TABLE 3.

Clinical Endpoints at 3- and 6-Month Follow-up

Follow-up intervalStudy patientsControlsP
3 mo
 Total115230
 Cure72 (62.6)151 (65.6)0.63
 Relapse3 (2.6)17 (7.4)0.09
 Persisting infection21 (18.2)3 (1.3)0.001
 Mortality19 (16.6)59 (25.7)0.06
 Relapse in S. aureus subgroup1/73 (1.4)13/146 (8.9)0.04
6 mo*
 Total115230
 Cure83 (72.2)154 (66.9)0.26
 Persisting infection8 (7)0<0.001
 Overall mortality22 (19.1)74 (32.2)0.007
 Infection-related mortality17 (14.8)56 (24.3)0.049
 Lost to follow-up2 (1.7)2 (0.9)0.60
  • * At 6-mo follow-up, 8 patients had died after relapse of infection in control group vs. 2 in study group.

  • Data presented in parentheses are percentages. P values are estimated by Fisher exact tests.