TABLE 2

Uptake Values of 99mTc-NbCEA5, 99mTc-Humanized Scaffold, and 99mTc-Humanized CEA5 Graft Based on Pinhole SPECT/Micro-CT at 1 Hour After Injection

Tissue99mTc-NbCEA5 (%IA/cm3)*99mTc-humanized scaffold (%IA/cm3)99mTc-humanized CEA5 graft (%IA/cm3)
Tumor7.09 ± 1.360.21 ± 0.056.15 ± 2.33
Muscle0.16 ± 0.130.26 ± 0.030.83 ± 0.06
Kidney88.01 ± 12.16136.66 ± 22.5587.05 ± 6.85
Lung1.49 ± 0.501.00 ± 0.192.19 ± 1.25
Liver2.19 ± 0.672.25 ± 1.093.09 ± 0.49
  • * Data are expressed as mean of 6 CEA-positive LS174T tumor–bearing mice ± SD.