TABLE 1

Concerns About Treatment of NHL Patients with 90Y-Ibritumomab Tiuxetan or 131I-Tositumomab

Mean value*
ConcernAcademiaNonacademiaP (proportional odds)
There is no treatment site of 131I-tositumomab or 90Y-ibritumomab tiuxetan convenient for my patients1.6082.418<0.01
It is or would be economically adverse for my practice to use 131I-tositumomab or 90Y-ibritumomab tiuxetan1.7752.209<0.01
The nuclear physicians are not too interested in treating patients with 131I-tositumomab or 90Y-ibritumomab tiuxetan2.052.672<0.01
Referring patients for 131I-tositumomab or 90Y-ibritumomab tiuxetan is too complicated2.1382.724<0.01
131I-tositumomab or 90Y-ibritumomab tiuxetan do not have enough reported randomized studies2.452.3430.8
131I-tositumomab or 90Y-ibritumomab tiuxetan is too expensive2.83.0530.21
There are possible unexpected late side effects (MDS)2.9383.1040.14
131I-tositumomab or 90Y-ibritumomab tiuxetan theoretically may cause bone marrow damage preventing further therapy (autologous stem cell transplantation)2.9883.2690.08
There are too many effective nonradioactive treatment alternatives for the NHL3.0132.9930.98
  • * 1 = no concern; 5 = major concern, with P value indicating significant difference.