TABLE 2

Hemodynamic Response to Adenosine Before and After β-Blockade

TestOff β-blockerOn β-blockerP
Rest
 Heart rate (bpm)73 ± 1157 ± 5<0.001
 Systolic blood pressure (mm Hg)139 ± 21136 ± 200.3
 Diastolic blood pressure (mm Hg)84 ± 1183 ± 120.8
 Rate–pressure product (×103 mm Hg · min−1)10.1 ± 2.37.7 ± 1.3<0.001
Peak stress
 Heart rate (bpm)97 ± 14*81 ± 9*<0.001
 Systolic blood pressure (mm Hg)147 ± 27*140 ± 240.04
 Diastolic blood pressure (mm Hg)83 ± 1180 ± 130.3
 Rate–pressure product (×103 mm Hg · min−1)14.3 ± 3.2*11.3 ± 2.4*<0.001
 Workload (watts)†5 (0–8.8)5 (0–10)0.2
 ΔHeart rate (bpm)24 ± 1124 ± 80.6
 ΔSystolic blood pressure (mm Hg)9 ± 165 ± 150.2
 ΔDiastolic blood pressure (mm Hg)−1 ± 10−3 ± 120.5
 ΔRate–pressure product (×103 mm Hg · min−1)4.2 ± 2.23.6 ± 1.90.07

  • ↵* P ≤ 0.001 vs. rest values.

  • ↵† Workload data summarized as median, with interquartile ranges in parentheses.

  • Exercise was not indicated in 1 patient because of left bundle branch block. bpm = beats per minute.