TABLE 1

Biodistribution (%ID/g) of ^99mTc-hTERT siRNA in Tumor-Bearing Mice

Tissue	0.5 h	1 h	2 h	4 h	6 h
Heart	0.76 ± 0.10	0.43 ± 0.05	0.41 ± 0.14	0.38 ± 0.10	0.32 ± 0.06
Liver	7.68 ± 0.84	3.08 ± 0.32	1.63 ± 0.38	1.56 ± 0.12	0.99 ± 0.05
Spleen	0.78 ± 0.15	0.50 ± 0.11	0.41 ± 0.07	0.36 ± 0.05	0.25 ± 0.08
Lung	1.36 ± 0.09	1.03 ± 0.23	0.98 ± 0.10	0.96 ± 0.08	0.65 ± 0.15
Kidney	9.31 ± 2.68	5.80 ± 2.80	4.47 ± 0.85	2.72 ± 0.63	1.99 ± 0.59
Stomach	3.06 ± 0.84	1.66 ± 0.10	1.44 ± 0.40	1.24 ± 0.27	1.20 ± 0.35
Small intestine	4.20 ± 1.93	2.77 ± 0.76	2.10 ± 1.24	0.95 ± 0.41	0.64 ± 0.07
Bladder	2.60 ± 0.78	2.08 ± 0.33	2.39 ± 0.41	3.42 ± 2.30	3.56 ± 0.49
Skeletal muscle	0.61 ± 0.15	0.31 ± 0.04	0.58 ± 0.49	0.22 ± 0.05	0.17 ± 0.01
Bone marrow	1.06 ± 0.21	0.59 ± 0.06	0.39 ± 0.19	0.19 ± 0.05	0.10 ± 0.03
Blood	0.88 ± 0.14	0.52 ± 0.03	0.44 ± 0.06	0.43 ± 0.08	0.40 ± 0.06
Tumor	1.08 ± 0.07	0.82 ± 0.16	0.71 ± 0.14	0.74 ± 0.15	0.97 ± 0.15