Ex Vivo Biodistribution of 11C-Choline in Atherosclerotic LDLR−/−ApoB100/100 and Control C57BL Mice at 10 Minutes After Intravenous Injection
| Organ | Atherosclerotic (n = 6) | Control (n = 5) | P |
|---|---|---|---|
| Aorta | 4.11 ± 1.13 | 2.21 ± 0.65 | 0.0016 |
| Blood | 0.72 ± 0.20 | 0.67 ± 0.38 | 0.7219 |
| Heart | 10.84 ± 3.80 | 8.61 ± 2.23 | 0.1109 |
| Kidney | 23.41 ± 8.00 | 32.63 ± 21.26 | 0.5121 |
| Liver | 9.53 ± 4.60 | 10.82 ± 6.20 | 0.8595 |
| Lung | 14.62 ± 6.01 | 12.94 ± 2.50 | 0.1981 |
| Muscle | 1.29 ± 0.44 | 1.80 ± 0.65 | 0.2226 |
| Pancreas | 8.44 ± 2.74 | 8.56 ± 3.09 | 0.6524 |
| Small intestine | 6.57 ± 2.12 | 5.91 ± 2.55 | 0.499 |
| Spleen | 4.51 ± 2.45 | 3.62 ± 2.03 | 0.4593 |
| Thymus | 3.11 ± 0.88 | 2.79 ± 1.62 | 0.4527 |
| White adipose tissue | 0.36 ± 0.12 | 0.40 ± 0.26 | 0.8119 |
Results are expressed as percentage of injected activity per gram of tissue (mean ± SD).