TABLE 1

Biodistribution of ^99mTc-Annexin V (Fraction of %ID/g) in Nontumor Organ or Tissues of BALB/c-RIII Mice at Baseline and at Sequential Times After Intravenous Administration of Paclitaxel (0.02 μg/g of Body Weight)

	Time (h)
Organ or tissue	Baseline	1	3	6	24
Blood	1.07 ± 0.0032	0.31 ± 0.0068	0.75 ± 0.0040	0.90 ± 0.0165	0.31 ± 0.0024
Heart	0.57 ± 0.0030	0.14 ± 0.0042	0.35 ± 0.0017	0.43 ± 0.0060	0.14 ± 0.0005
Lung	1.46 ± 0.0123	0.32 ± 0.0122	1.12 ± 0.0123	0.97 ± 0.0151	0.30 ± 0.0011
Thyroid	0.24 ± 0.0007	0.04 ± 0.0004	0.06 ± 0.0011	0.11 ± 0.0017	0.24 ± 0.0005
Stomach	0.37 ± 0.0015	0.03 ± 0.0004	0.07 ± 0.0009	0.31 ± 0.0017	0.26 ± 0.0016
Small bowel	0.40 ± 0.0011	0.06 ± 0.0124	0.27 ± 0.0027	1.06 ± 0.0053	0.09 ± 0.0024
Liver	1.28 ± 0.0189	1.68 ± 0.0316	2.87 ± 0.0247	1.11 ± 0.0495	0.51 ± 0.0022
Spleen	0.46 ± 0.0146	1.31 ± 0.0151	0.78 ± 0.0148	0.88 ± 0.0165	0.49 ± 0.0024
Kidney	15.86 ± 0.0518	11.65 ± 0.0816	13.28 ± 0.301	9.65 ± 0.1359	7.33 ± 0.0220
Skin	0.57 ± 0.0046	0.12 ± 0.0053	0.38 ± 0.0023	0.54 ± 0.0124	0.15 ± 0.0010
Muscle	0.28 ± 0.0023	0.05 ± 0.0019	0.14 ± 0.0008	0.28 ± 0.0039	0.07 ± 0.0001
Bone	0.18 ± 0.0025	0.09 ± 0.0033	0.25 ± 0.0017	0.40 ± 0.0058	0.07 ± 0.0009
Normal breast	0.26 ± 0.0034	0.13 ± 0.0017	0.14 ± 0.0014	0.19 ± 0.0027	0.14 ± 0.0013

Data are expressed as median ± SD.