Patients' Characteristics
| Patient no. | Histology and grade | Lesion location in PET | Cycles of EIA | Resection before EIA | Response Evaluation Criteria in Solid Tumors | Histopathologic response (<10% viable cells) | Treatment after EIA |
|---|---|---|---|---|---|---|---|
| 1 | Synovial sarcoma, II | Upper leg | 4 | R1 | CR | Response | R0 + IORT |
| 2 | Leiomyosarcoma, III | Upper leg | 4 | R1 | PR | Response | R0 + IORT |
| 3 | Synovial sarcoma, III | Mediastinum | 6 | R2 | SD | No surgery | RTx |
| 4 | Liposarcoma, III | Retroperitoneum | 6 | R2 | SD | Response | R1 + IORT |
| 5 | Fibrosarcoma, III | Upper leg | 4 | R1 | CR | Response | R0 + IORT |
| 6 | Fibrosarcoma, II | Upper leg | 2 | R2 | SD | Nonresponse | R0 |
| 7 | Fibrosarcoma, II | Upper leg | 4 | No | SD | NA | R0 + IORT |
| 8 | Synovial sarcoma, II | Upper arm | 4 | R1 | CR | Response | R0 + IORT |
| 9 | Liposarcoma, II | Upper leg | 5 | No | PR | Response | R0 |
| 10 | Liposarcoma, III | Thyroid gland | 4 | R2 | PR | Response | R1 |
| 11 | Epitheloid sarcoma, III | Arm/shoulder | 4 | No | PR | Response | R0 + RTx |
| 12 | Liposarcoma, III | Thoracic wall | 4 | R0 | SD | No surgery | No surgery |
| 13 | MFH, III | Thoracic wall | 4 | No | SD | Nonresponse | R0 + IORT |
| 14 | Liposarcoma, II | Upper leg | 4 | No | SD | Nonresponse | R1 + RTx |
| 15 | Rhabdomyosarcoma, II | Sinus maxillaris | 4 | No | PR | Response | R1 |
| 16 | MFH, II | Lower leg | 5 | No | PR | Nonresponse | R1 |
| 17 | Haemangiopericytoma, II | Pelvic area | 8 | No | SD | No surgery | No surgery |
| 18 | Liposarcoma, III | Upper leg | 4 | No | SD | Nonresponse | R0 + IORT |
| 19 | Liposarcoma, III | Retroperitoneum | 4 | No | SD | Nonresponse | R1 + IORT |
| 20 | Liposarcoma, II | Upper leg | 4 | No | SD | Nonresponse | R0 + IORT |
| 21 | MFH, III | Upper leg | 4 | No | SD | Nonresponse | Rx + IORT |
| 22 | Synovial sarcoma, III | Pelvic area | 4 | No | SD | Nonresponse | R1 + IORT |
| 23 | Synovial sarcoma, III | Upper leg | 4 | R2 | PR | Response | R0 + IORT |
| 24 | Leiomyosarcoma, III | Thoracic wall | 4 | R0–1 | PD | Nonresponse | R0 + IORT |
| 25 | Synovial sarcoma, III | Upper leg | 4 | No | SD | NA | R0 + IORT |
| 26 | Liposarcoma, II | Upper leg | 4 | No | SD | Nonresponse | R0 + IORT |
| 27 | Liposarcoma, II | Upper leg | 4 | No | SD | Response | R0 + IORT |
| 28 | Synovial sarcoma, III | Lower leg | 4 | No | SD | Nonresponse | R0 + IORT |
| 29 | Liposarcoma, III | Upper leg | 2 | No | PD | Response | R0 + IORT |
| 30 | MFH, III | Upper leg | 4 | No | SD | NA | R0 + IORT |
| 31 | Liposarcoma, II | Upper leg | 4 | No | SD | Nonresponse | R0 + IORT |
R1 = R1 resection; CR = complete responder; R0 = R0 resection; IORT = intraoperative radiation treatment; PR = partial responder; R2 = R2 resection; SD = stable disease; RTx = radiation treatment; NA = not applicable; MFH = malignant fibrous histocytoma; Rx = Rx resection; PD = progressive disease.