TABLE 4

Parameter Modeling Results

Parameter	Mean estimate	SD	COV
Axial bone metastases (n = 20)
K₁^*	0.166^†	0.084	50%
V_D^‡	2.81	2.60	92%
K₃^§	0.288	0.257	89%
K₄^§	0.052	0.107	205%
Ki^*	0.103^†	0.048	47%
Ki/K₁	0.673	0.218	32%
Normal vertebrae (n = 20)
K₁^*	0.091^†	0.035	38%
V_D^‡	1.94	2.52	130%
K₃^§	0.165	0.107	65%
K₄^§	0.067	0.121	181%
Ki^*	0.052^†	0.020	38%
Ki/K₁	0.597	.202	34%

↵* mL·cm⁻³·min⁻¹.
↵† Metastases K₁ and Ki values were significantly different from their normal values (P < 0.001).
↵‡ mL·cm⁻³.
↵§ min⁻¹.