IC10 and IC50 Values for Methotrexate, Paclitaxel, and Doxorubicin on MDA-MB-231, 231-H2N, TrR1, and TrR2 Human Breast Cancer Cells
| Cell line | Methotrexate* | Paclitaxel | Doxorubicin |
|---|---|---|---|
| MDA-MB-231 | |||
| IC10 (μmol/L) | 1.01 ± 0.01 | 0.07 ± 0.03 | 0.19 ± 0.08 |
| IC50 (μmol/L) | 103.3 ± 13.4 | 0.32 ± 0.13 | 1.26 ± 0.39 |
| 231-H2N | |||
| IC10 (μmol/L) | 12.0 ± 0.23 | 0.14 ± 0.10 | 0.02 ± 0.004 |
| IC50 (μmol/L) | 120.8 ± 23.3 | 1.36 ± 0.24 | 0.16 ± 0.04 |
| TrR1 | |||
| IC10 (μmol/L) | 0.01 ± 0.001 | 0.12 ± 0.03 | 0.03 ± 0.01 |
| IC50 (μmol/L) | 0.13 ± 0.01 | 2.01 ± 0.47 | 0.55 ± 0.25 |
| TrR2 | |||
| IC10 (μmol/L) | 1.13 ± 0.16 | 0.02 ± 0.01 | 0.02 ± 0.003 |
| IC50 (μmol/L) | 102.4 ± 10.7 | 0.27 ± 0.06 | 0.21 ± 0.08 |
↵* Values were reported previously in Costantini et al. (16).
Results are expressed as mean ± SEM of 3 measurements performed in duplicate.