TABLE 3

Comparison of Projected SF^* Using Various Dose Calculation Methods

Cell geometry	Dose calculation method	Calculated dose to cell nucleus (Gy)	Dose-projected SF	Corrected SF	RE (%)
Cell monolayer	MCNP	0.59	0.75	0.64	3.1
Single cell	MCNP	0.47	0.80	0.67	8.1
	Goddu et al. (8)	0.46	0.80	0.67	8.1
	Goddu et al. (9)	0.45	0.80	0.67	8.1
	Farragi et al. (11)	0.49	0.79	0.67	8.1
Cell cluster	MCNP	2.2	0.33	0.28	−54
	Farragi et al. (11)	2.8	0.24	0.20	−67

↵* MDA-MB-468 cells were treated with ¹¹¹In-DTPA-hEGF (3.2 MBq/mL; 21 nM) for 1 h and had experimental SF of 0.62 (2).