Patient Characteristics and Results
| Findings | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Type of malignancy | n | Age (y) | Injected dose (MBq) | Planar images | SPECT/CT | Surgery | Intraoperative localization | Postoperative course | Pathology |
| Prostate cancer | 8 | Median: 68; range: 56–71 | Median: 205; range: 147–239 | 8 midabdominal SNs; 16 pelvic or presacral SNs | 8 SNs around aortic bifurcation (exact localization); localization of 20 other SNs | Laparoscopic sentinel lymphadenectomy | Detection and localization of all SNs with portable γ-camera and probe | Uncomplicated: 7 pts; lymphocele: 1 pt | Paraaortic SN positive: 1 pt; parailiac SN positive: 2 pts |
| Renal cell carcinoma | 6 | Median: 54; range: 45–59 | Median: 224; range: 95–243 | 4 midabdominal SNs; 1 parasternal SN; nonvis: 2 pts | 8 para- and interaortocaval SNs (exact localization); 1 parasternal SN | Laparoscopic nephrectomy and sentinel lymphadenectomy: 1 pt; open procedure: 5 pts | Visualization of SN with portable γ-camera: 3 pts; detection possible only with γ-probe: 3 pts; detection of additional hot node in 1 pt* | Uncomplicated: 4 pts; infected wound: 1 pt; cicatricial hernia of nephrectomy wound:1 pt | All SNs negative |
| Testicular cancer | 4 | Median: 32; range: 31–40 | Median: 77; range: 59–97 | 7 midabdominal SNs | 5 interaortocaval SNs; 2 left paraaortic SNs; 1 SN along testicular vein (exact localization); localization of 1 parailiac SN | Laparoscopic sentinel lymphadenectomy | Detection and localization of all SNs with portable γ-camera and probe | Uncomplicated: 3 pts; hydronephrosis:1 pt | All SNs negative |
↵* Two paraaortic sentinel nodes were found and removed during surgery, whereas preoperative SPECT/CT had visualized only 1 paraaortic sentinel node.
Nonvis = nonvisualization; Pt = patient; SN = sentinel node.