Association Between Possible Influences on Study Quality and Between-Study Heterogeneity of Diagnostic Performance
| QUADAS component | Coefficient | 95% CI | P | I-squared |
|---|---|---|---|---|
| Were selection criteria clearly described? | 0 | −3.0 to 3.1 | 0.989 | 9.6% |
| Is the time between reference standard and index test short enough? | −1.8 | −5.3 to 1.8 | 0.256 | 0% |
| Did the whole sample or a random selection of the sample receive verification using a reference standard of diagnosis? | −1.6 | −4.3 to 1.0 | 0.171 | 0% |
| Was the execution of the index test described in sufficient detail to permit its replication? | −2.0 | −8.1 to 4.0 | 0.405 | 1.8% |
| Was the execution of the reference standard described in sufficient detail to permit its replication? | −1.9 | −7.6 to 3.7 | 0.423 | 0% |
| Were the index test results interpreted without knowledge of the results of the reference standard? | −1.5 | −4.0 to 1.1 | 0.199 | 0% |
| Were withdrawals from the study explained? | −0.3 | −3.9 to 3.2 | 0.826 | 9.2% |
Component that shows same score in all studies was dropped because of colinearity.