TABLE 1

GBEF, SD, Lower Limits of Normal for 2 and 3 SDs, CV, and 95% CIs for 3 Different Infusion Methods at 4 Intervals in Healthy Subjects

Infusion duration (min)Time of GBEF calculation (min)No. of subjectsMean GBEF (%)GBEF lower limits of normal (%)
SD (%)-2 SDs-3 SDsCV (%)
1515605729−1−3051.66 (43.79, 63.01)
3045672713−1440.46 (33.49, 51.10)
4545662614−1239.91 (33.05, 50.42)
6045682423035.21 (29.15, 44.48)
3015604428−12−4062.75 (53.19, 76.53)
3060712423−134.49 (29.23, 42.06)
4545732327431.30 (25.91, 39.53)
60457421321129.11 (24.10, 36.77)
6015603424−14−3871.38 (60.52, 87.08)
3060642318−535.81 (30.36, 43.69)
45607819402124.00 (20.35, 29.28)
60608416523618.55 (15.73, 22.64)
  • Data in parentheses are 95% CIs.