TABLE 1

Brief Summary of In Vivo Imaging of RNAi

ModalityImaging delivery or effect?Image tagLabeling gene or carrier?Clinical potentialReference
FluorescenceBothFluorescent dye, QD, GFP, etc.Both+8–11,13,26
MRIDeliveryIron oxideCarrier++13
SPECTDelivery99mTc and 111InBoth+++14–16
PETDelivery18F and 64CuGene+++17,18
BLIEffectLuciferasesNANone17,20–25
MRSEffectChemical shiftNA++27

  • NA = not applicable.