Summary and Comparison of Functionalities of COMKAT Distributions
| Function | COMKAT on MATLAB | Compiled COMKAT application |
|---|---|---|
| COMKAT GUI | ||
| Loading of input functions from files | Yes | Yes |
| Simulation of model output | Yes | Yes |
| Creation of new kinetic models | Yes | No |
| Parameter estimation | Yes | Yes |
| Loading of tissue time–activity curves from files | Yes | Yes |
| Loading of tissue time–activity curves from COMKAT image tool | Yes | Yes |
| Calculation of parametric images | Yes | Yes |
| Distributed computing for parametric imaging* | Yes | No |
| COMKAT image tool | ||
| Support for multiple image formats (Table 2) | Yes | Yes |
| Image display and contrast adjustments | Yes | Yes |
| Frame summation | Yes | Yes |
| Spatial filtering | Yes | Yes |
| Drawing of ROIs or volumes of interest | Yes | Yes |
| Image coregistration | Yes | Yes |
| Image translation and rotation | Yes | Yes |
| Image reslicing in arbitrary orientations | Yes | Yes |
| MATLAB scripting with COMKAT command-line functions | Yes | No |
| Available for Windows, Linux, and MacOS X† | Yes | Yes |
| COMKAT licensing | Free for academic research use | Free for academic research use |
| MATLAB licensing | Requires MATLAB installation and licenses | Requires MATLAB Compiler Runtime (no licensing fees) |