Absolute Mean, RC, and Percentage Difference with RC for 18F-FDG and 18F-FLT
Radiotracer | VOI | n (pairs) | Mean absolute difference (mL) | RC (1.96 × SD) (mL) | Mean percentage difference | RC (1.96 × SD) (%) |
18F-FDG | ||||||
For total lesions | A41% | 18 | 1.8 | 5.9 | 22.6 | 44.4 |
50% | 18 | 2.0 | 6.0 | 24.3 | 52.5 | |
A50% | 32 | 1.8 | 4.2 | 35.5 | 62.4 | |
A70% | 34 | 0.4 | 1.1 | 43.7 | 71.1 | |
For lesions < 4.2 mL | A41% | 7 | 0.7 | 1.3 | 28.0 | 47.7 |
50% | 8 | 0.6 | 1.4 | 25.8 | 57.7 | |
A50% | 13 | 0.7 | 1.0 | 39.8 | 64.5 | |
A70% | 31 | 0.3 | 0.8 | 46.2 | 72.0 | |
For lesions > 4.2 mL | A41% | 9 | 2.5 | 7.8 | 12.1 | 21.9 |
50% | 9 | 2.8 | 7.9 | 16.2 | 28.9 | |
A50% | 12 | 2.9 | 5.4 | 21.3 | 37.2 | |
A70% | 3 | 1.4 | 2.2 | 17.2 | 36.5 | |
18F-FLT | ||||||
For total lesions | A41% | 10 | 1.2 | 2.2 | 24.1 | 34.9 |
50% | 12 | 1.0 | 2.1 | 21.0 | 39.4 | |
A50% | 19 | 1.4 | 6.3 | 19.7 | 50.2 | |
A70% | 20 | 0.5 | 0.9 | 56.8 | 94.0 | |
For lesions < 4.2 mL | A41% | 6 | 0.7 | 0.9 | 29.5 | 30.9 |
50% | 7 | 0.5 | 0.9 | 24.4 | 33.2 | |
A50% | 12 | 0.3 | 0.9 | 16.0 | 33.2 | |
A70% | 20 | 0.5 | 1.5 | 56.8 | 94.0 | |
For lesions > 4.2 mL | A41% | 4 | 2.0 | 2.8 | 16.1 | 39.0 |
50% | 5 | 1.6 | 2.8 | 16.2 | 49.2 | |
A50% | 7 | 3.2 | 9.6 | 25.9 | 72.7 | |
A50%* | 6 | 1.4 | 2.0 | 12.2 | 16.0 | |
A70% | 0 | — | — | — | — |
↵* Data, with exclusion of heterogeneous lesion that highly affected outcome.
None of mean percentage differences were significantly different from 0. Percentage differences were calculated by the following formula: |volume scan 1 – volume scan 2|/(0.5 [volume scan 1 + volume scan 2]) × 100.