TABLE 1

Patient Population, Indication for ⁶⁸Ga-Citrate PET/CT, and Final Diagnosis

					SUVmax		SUVmean of normal surrounding bone marrow
Patient no.	Sex	Age (y)	Indication for PET/CT	Timing of PET/CT^*	Before therapy	After therapy	Before therapy	After therapy	Final diagnosis
1	F	64	Acute osteomyelitis of ankle	After therapy		1.4^†		1.4^‡	TN
2	F	63	acute osteomyelitis of elbow	Before and after therapy	4.8	3.1	1.1	1.3^‡	TP, FP
3	M	18	Acute osteomyelitis of tibia	Before therapy	4.3		2		TP
4	M	34	Acute osteomyelitis of tibia	Before therapy	2.6		0.8		TP
5	F	32	Acute osteomyelitis of tibia	Before therapy	5.5		0.9		TP
6	M	29	Acute osteomyelitis of tibia	Before therapy	4.4		1^‡		TP
7	M	58	Acute osteomyelitis of tibia	Before therapy	2.4		1.7		FP (lymphoma)
8	M	44	Acute osteomyelitis of tibia	Before and after therapy	3.3	1.5^†	2	1.5	TP, TN
9	F	60	Acute osteomyelitis of tibia	Before therapy	2.6		0.9		TP
10	M	20	Acute osteomyelitis of tibia	Before therapy	4		1.3		TP
11	M	18	Acute osteomyelitis of tibia	Before and after therapy	3.5	1.8^†	2.4	1.8	TP, TN
12	M	54	Acute osteomyelitis of acetabulum	Before therapy	6		0.9		TP
13	M	19	Acute osteomyelitis of hip	Before therapy	8		0.8		TP
14	F	20	Acute osteomyelitis of hip	Before therapy	7.3		2		FP (osteoblastoma)
15	M	51	Acute osteomyelitis of humerus	Before and after therapy	4.1	5.6	1.7	2.1^‡	TP, TP
16	M	22	Acute osteomyelitis of humerus	Before and after therapy	2.5	1.4^†	1.2	1.4	TP, TN
17	M	51	Acute osteomyelitis of knee (proximal tibia)	Before and after therapy	3.1	1.6^†	0.8	1.6^‡	TP, TN
18	M	24	Acute osteomyelitis of tibia	Before and after therapy	2	1.3^†	1	1.3	TP, TN
19	M	65	Chronic osteomyelitis of pelvis	Before therapy	7		2		FP (lymphoma)
20	F	68	Chronic osteomyelitis of pelvis	Before therapy	1^†		1^‡		TN
21	F	47	Chronic osteomyelitis of femur	After therapy		1.9^†		1.9^‡	TN
22	M	23	Chronic osteomyelitis of pelvis	Before therapy	4		1.1		TP
23	M	41	Diskitis	Before and after therapy	8.6	2.9^†	2.1	2.9	TP, TN
24	F	49	Diskitis	Before therapy	5.3		2.2		TP
25	F	10	Diskitis	Before therapy	4.1		4.1		TN (SUVmax is high but comparable to normal bone marrow)
26	F	71	Diskitis	Before therapy	2.2		1.7		TP
27	F	70	Diskitis	Before therapy	1.2^†		1.2		TN
28	M	53	Diskitis	Before therapy	6		1.5		TP
29	F	33	Diskitis	Before and after therapy	3.7	1.9^†	2.3	1.9	TP, TN
30	M	52	Diskitis	Before therapy	2^†		2		TN
31	F	50	Diskitis	Before therapy	5.6		1.8		TP
Mean		42			4.6		1.5^¶

↵* Mean: 9 before and after therapy, 21 before therapy only, and 1 after therapy only.
↵† Normal value.
↵‡ Bone implant or prosthesis; mean = 7.
↵¶ Patient 18 was excluded.
TN = true-negative; TP = true-positive; FP = false-positive.