TABLE 1

Radiation Dose Comparison Between 18F-Fluoride and 99mTc-MDP

PatientIntravenous administered activityOrgan receiving largest radiation doseEffective dose
18F-fluoride
 Adult185–370 MBq (5–10 mCi)Bladder*: 0.22 mGy/MBq (0.81 rad/mCi)0.024 mSv/MBq (0.089 rem/mCi)
 Child (5 y old)2.22 MBq/kg (0.06 mCi/kg)Bladder*: 0.61 mGy/MBq (2.3 rad/mCi)0.086 mSv/MBq (0.32 rem/mCi)
99mTc-MDP
 Adult740–1,110 MBq (20–30 mCi)Bone surfaces: 0.063 mGy/MBq (0.23 rad/mCi)0.0057 mSv/MBq (0.021 rem/mCi)
 Child (5 y old)7–11 MBq/kg (0.2–0.3 mCi/kg)Bone surfaces: 0.22 mGy/MBq (0.81 rad/mCi)0.025 mSv/MBq (0.092 rem/mCi)
  • * Voiding interval, 3.5 h. Changes in bladder wall dose are approximately linear with changes in voiding interval; for voiding interval of 2.0 h, dose to bladder wall would change by factor of 2/3.5.

  • Data are from the International Commission on Radiological Protection (42,43).