Biodistribution of Antisense Probe in Mice Bearing MCF-7 Xenografts
| Time (h) | ||||
| Biodistribution (%ID/g) | 1 | 2 | 4 | 6 |
| Blood | 7.42 ± 1.01 | 5.56 ± 0.42 | 2.24 ± 0.22 | 1.97 ± 0.18 |
| Heart | 2.98 ± 0.23 | 2.83 ± 0.29 | 1.95 ± 0.17 | 1.32 ± 0.25 |
| Lung | 4.56 ± 0.38 | 3.44 ± 0.32 | 3.09 ± 0.41 | 2.16 ± 0.29 |
| Liver | 11.26 ± 1.97 | 10.74 ± 1.88 | 6.86 ± 0.77 | 3.42 ± 0.54 |
| Spleen | 6.92 ± 0.91 | 5.28 ± 0.71 | 3.67 ± 0.44 | 1.32 ± 0.27 |
| Kidney | 13.76 ± 2.47 | 9.83 ± 1.80 | 5.59 ± 0.74 | 3.47 ± 0.57 |
| Small intestine | 5.29 ± 0.71 | 4.29 ± 0.47 | 1.78 ± 0.37 | 0.59 ± 0.12 |
| Skeletal muscle | 4.04 ± 0.87 | 3.83 ± 0.51 | 2.52 ± 0.47 | 0.67 ± 0.21 |
| Thyroid | 4.16 ± 0.43 | 3.42 ± 0.37 | 1.67 ± 0.21 | 1.16 ± 0.27 |
| Tumor | 9.21 ± 1.37 | 8.94 ± 1.17 | 8.66 ± 1.09 | 8.10 ± 1.07 |
Each value represents average of 3 mice ± SD and is expressed as %ID radioactivity per gram of organ or tissue.