TABLE 2

Radiation Dose Estimates for 18F-PBR06 Determined in 7 Healthy Subjects

Radiation dose
Target organμSv/MBqmrem/mCi
Adrenals16.059
Brain10.037
Breasts8.331
Gallbladder wall367.01,360
Lower large intestine wall10.539
Small intestine13.349
Stomach wall13.048
Upper large intestine wall15.256
Heart wall22.583
Kidneys39.3146
Liver46.1170
Lungs36.5135
Muscle9.535
Ovaries11.242
Pancreas18.669
Red marrow17.665
Osteogenic cells21.680
Skin6.825
Spleen64.5239
Testes7.929
Thymus10.037
Thyroid8.531
Urinary bladder wall*31.0115
Uterus11.944
Effective dose18.569
  • * Determined from dynamic urinary bladder model with voiding interval of 2.4 h.