TABLE 1.

Reproducibility of Tumor Measurements Using Dynamic H₂¹⁵O PET/CT Scans

			Repeatability coefficient
Measurement	ICC	95% CI	Absolute value	Relative value (%)
Tumor perfusion (F)
CT-based VOI, NLR	0.997	0.986–0.999	0.030 mL·cm⁻³·min⁻¹	15.8
Parametric VOI, NLR^*^†	0.980	0.915–0.996	0.074 mL·cm⁻³·min⁻¹	19.9
Direct parametric VOI^*^‡	0.977	0.901–0.995	0.084 mL·cm⁻³·min⁻¹	40.9
Volume of distribution (V_T)
CT-based VOI, NLR	0.880	0.560–0.972	0.20 mL·cm⁻³	47.3
Parametric VOI, NLR^*^†	0.871	0.532–0.969	0.19 mL·cm⁻³	37.0
Direct parametric VOI^*^‡	0.908	0.649–0.979	0.17 mL·cm⁻³	36.8
Tumor size
CT-based VOI	0.998	0.993–1.000	14.2 cm³	27.3
Parametric VOI^*	0.811	0.367–0.954	29.5 cm³	98.6

↵* Parametric perfusion images with 10-mm filter were used.
↵† Values were obtained by projecting parametric-based VOI onto dynamic H₂¹⁵O images.
↵‡ Values were obtained by direct extraction from parametric image.
n = 9 lesions.