Summary of Average S/C-1 Ratios
| Experiment | Dose blocker (mg/kg) | S/C-1 ratio | % Reduction, compared with baseline* |
| Baseline (n = 2) | 2.9 | ||
| Self-block (n = 1) | 2.5 | 0.4 | ∼86 |
| TP-10 (n = 1) | 5 | 0.5 | ∼83 |
| MP-10 (n = 2) | 5 | 1.4 | ∼52 |
| 1 | 2.5 | ∼14 | |
| 0.5 | 2.7 | ∼7 |
↵* Calculation based on S/C-1 ratios.
Data were obtained from baseline small-animal PET imaging of 18F-JNJ41510417 and from pretreatment self-blocking and blocking experiments with TP-10 and MP-10. S/C-1 ratios are averaged values from 32 min after tracer injection (when maximum is reached) until 75 min after tracer injection (when S/C-1 ratio starts decreasing). Data are expressed as mean when n > 1.