Biodistribution of 18F-JNJ41510417 in Normal Rats at 2, 30, and 60 Minutes After Tracer Injection
| Percentage of injected dose* | |||
| Body part | 2 min | 30 min | 60 min |
| Urine | 0.1 ± 0.0 | 0.2 ± 0.0 | 0.9 ± 0.2 |
| Kidneys | 6.9 ± 0.5 | 1.8 ± 0.1 | 1.3 ± 0.1 |
| Liver | 41.1 ± 2.4 | 52.3 ± 4.6 | 42.6 ± 2.3 |
| Spleen + Pancreas | 1.9 ± 0.1 | 0.6 ± 0.1 | 0.4 ± 0.0 |
| Lungs | 2.4 ± 0.1 | 0.4 ± 0.0 | 0.3 ± 0.0 |
| Heart | 0.9 ± 0.1 | 0.2 ± 0.0 | 0.2 ± 0.0 |
| Stomach | 1.7 ± 0.3 | 5.1 ± 2.0 | 13.7 ± 1.4 |
| Intestines | 9.4 ± 0.6 | 10.8 ± 4.9 | 12.5 ± 2.5 |
| Cerebrum | 0.447 ± 0.009 | 0.266 ± 0.003 | 0.257 ± 0.007 |
| Cerebellum | 0.101 ± 0.015 | 0.035 ± 0.003 | 0.031 ± 0.002 |
| Blood | 4.0 ± 0.3 | 2.0 ± 0.2 | 2.1 ± 0.2 |
| Remainder | 32.8 ± 2.4 | 26.4 ± 1.5 | 26.0 ± 1.3 |
↵* Calculated as counts per minute in organ/total counts per minute recovered.
Data are expressed as mean ± SD; n = 3 per time point.