TABLE 1.

Characteristics and Treatment Response of Subjects Treated with ⁹⁰Y-DOTATOC

		Lansky Play Scale or Karnofsky score				Total dose (GBq)		Follow-up (mo)
Subject no.	Diagnosis	Before	After	Age (y)	Cohort	Total dose (GBq)	Response	Follow-up (mo)
1	Pinealoblastoma	60	0	5	1	0.74	PD	DOD (0)
2	Paraganglioma	90	90	15	1	4.66	Stable disease	AWD (84)
3^*	Anaplastic astrocytoma	90	100	11	1	6.33	PR	DOD (23)
4	Neuroblastoma	80	70	12	1	4.92	Stable disease	DOD (2)
5^*	Gastrinoma	90	100	8	1	4.77	PR	NED (68)
6^*	Bronchial carcinoid	90	100	17	2	10.36	Stable disease	AWD (63)
7^*	Gastrinoma	90	100	16	2	9.81	MR	NED (56)
8	Medulloblastoma	80	70	11	2	1.70	Withdrew	DOD (10)
9	Neuroblastoma	90	80	4	2	1.15	Withdrew	DOD (9)
10	Gastrinoma	100	100	24	2	9.07	Stable disease	DOD (22)
11	Multiple endocrine neoplasia IIB	90	90	18	3	7.40	Stable disease	AWD (39)
12	Gastrinoma	100	100	15	3	8.88	MR	AWD (39)
13	Paraganglioma	70	90	18	3	8.39	MR	AWD (22)
14	Bronchial carcinoid	80	90	23	3	10.77	MR	AWD (22)
15	Choroid plexus carcinoma	80	0	2	3	0.89	PD	DOD (1)
16	Pancreatic NET	80	100	16	3	8.14	MR	AWD (17)
17	Paraganglioma	80	100	14	3	10.80	Stable disease	AWD (17)

↵* Received fourth dose with permission of Food and Drug Administration and Institutional Review Board.
DOD = died of disease; AWD = alive with disease; NED = no evidence of disease.