Esophageal carcinomas | Mandard system (24) | No or only a few scattered residual tumor cells (regression scores 1 and 2) |
Bone tumors | Salzer–Kuntschik system (25) | Salzer–Kuntschik grades I–III: less than 10% residual vital tumor area (grade I, 0%; II, single vital areas; and III, <10%) |
Breast cancer (7) | Previously described criteria (26,27) | Macroscopic (absence of macroscopically visible tumor) or microscopic (histologic absence of invasive tumor cells) response |
Breast cancer (13) | — | No recognizable invasive tumor cells (ductal carcinoma in situ may be present) |
Head and neck cancer (11) | — | No viable residual tumor cells in any section |
Non–small cell lung cancer | — | Tissue negative for malignant cells |
Locally advanced rectal cancer | — | Complete regression or rare residual cancer cells |
Gynecologic cancer | — | No tumor (complete response) or residual microscopic disease only |