Subject Characteristics
| Values for subjects in the following groups*: | ||||||||
|---|---|---|---|---|---|---|---|---|
| HC (n = 10) | MCI (n = 10) | AD (n = 12) | ||||||
| Variable | Mean | SD | Mean | SD | Mean | SD | F | P |
| Age (y) | 72.5 | 10.1 | 73.9 | 5.8 | 75.0 | 8.9 | 0.23 | 0.794 |
| Education (y) | 15.4 | 2.7 | 15.3 | 2.1 | 13.2 | 3.2 | 2.36 | 0.113 |
| WRAT-3 reading | 109.9 | 8.0 | 108.5 | 10.2 | 101.3 | 17.9 | 1.35 | 0.275 |
| WAIS-III VIQ | 118.2 | 12.2 | 108.1 | 15.3 | 90.9 | 21.8 | 7.05† | 0.003 |
| WAIS-III PIQ | 114.1 | 14.3 | 107.7 | 10.1 | 81.3 | 17.1 | 16.50‡ | <0.001 |
| WAIS-III FSIQ | 119.5 | 13.1 | 108.8 | 13.4 | 85.5 | 19.9 | 13.00‡ | <0.001 |
| CDR | 0.00 | 0.00 | 0.50 | 0.00 | 1.00 | 0.52 | 22.51§ | <0.001 |
| MMSE | 29.4 | 0.5 | 26.8 | 2.3 | 20.4 | 5.9 | 17.12‡ | <0.001 |
| CSDD | 0.0 | 0.0 | 1.2 | 1.6 | 2.3 | 2.9 | 4.49† | 0.020 |
| Modified Hachinski Ischemic Score | 0.4 | 0.5 | 0.7 | 0.5 | 0.3 | 0.5 | 2.42 | 0.107 |
↵* There were 4 women and 6 men each in HC and MCI groups; there were 8 women and 4 men in AD group. χ2 = 2.13; P = 0.344.
↵† AD group differed significantly from HC group; MCI group did not differ from AD or HC group.
↵‡ AD group differed significantly from MCI and HC groups; MCI group did not differ from HC group.
↵§ All groups differed significantly.
Variables are reported as scores, unless otherwise indicated. WRAT-3 reading = Wide-Range Achievement Test, third edition, reading subtest (standard score) as estimate of premorbid intelligence; WAIS-III = Wechsler Adult Intelligence Scale, third edition; VIQ = verbal IQ; PIQ = performance IQ; FSIQ = full-scale IQ.
F and P values were from ANOVAs, with exception of those for WAIS-III, which were from ANCOVAs controlling for sex and education.