Comparison of K1 and VT Estimates Obtained from 1-Tissue Model for 11C-DPA-713 (n = 5) and 11C-R-PK11195 (n = 2)
| K1 value | VT value | |||
|---|---|---|---|---|
| ROI | DPA-713 | PK11195 | DPA-713 | PK11195 |
| Caudate | 0.25 ± 0.05 (4.0) | 0.020 ± 0.012 (24.9) | 3.08 ± 0.57 (3.8) | 0.25 ± 0.09 (23.1) |
| Cerebellar cortex | 0.27 ± 0.03 (4.8) | 0.025 ± 0.016 (12.5) | 3.88 ± 0.85 (4.5) | 0.32 ± 0.08 (11.9) |
| Frontal | 0.27 ± 0.05 (4.3) | 0.023 ± 0.013 (14.6) | 4.11 ± 0.84 (4.1) | 0.33 ± 0.10 (13.9) |
| Pons | 0.20 ± 0.07 (5.4) | 0.019 ± 0.016 (23.1) | 5.06 ± 0.83 (5.5) | 0.42 ± 0.13 (33.3) |
| Putamen | 0.29 ± 0.06 (4.8) | 0.026 ± 0.015 (10.3) | 3.54 ± 0.56 (4.5) | 0.34 ± 0.06 (9.5) |
| Temporal | 0.23 ± 0.04 (4.5) | 0.016 ± 0.011 (22.0) | 3.69 ± 0.69 (4.3) | 0.40 ± 0.08 (29.4) |
| Thalamus | 0.27 ± 0.04 (5.0) | 0.025 ± 0.013 (12.0) | 4.72 ± 0.90 (4.8) | 0.42 ± 0.07 (11.9) |
Data are mean ± SD. Mean COV (percentage standard fitting error) is shown in parentheses.