Changes of NIS mRNA Expression in Thyroid Cells Irradiated with 123I, 131I, 99mTc, or 211At to Absorbed Dose of 0.5 Gy During 6 Hours, on Days 1 and 5 After Irradiation
| NIS mRNA downregulation (% of control) | ||
|---|---|---|
| Radionuclide | 1 d | 5 d |
| 131I | NS | 80 |
| 123I | 55 | NS |
| 99mTc | NS | 34 |
| 211At | 26 | 61 |
qRT-PCR data are presented as percentage downregulation, compared with matched nonirradiated controls. NS indicates no statistically significant difference from controls, P < 0.001.