Per-Patient Analysis of Systemic and Coronary Hemodynamics
| Reproducibility (mean ± SD, n = 22) | Accuracy (mean ± SD, n = 20) | |||
|---|---|---|---|---|
| Parameter | 82Rb study 1 | 82Rb study 2 | 82Rb | 13N ammonia |
| Systemic hemodynamics | ||||
| HR at rest | 65 ± 8 | 65 ± 9 | 64 ± 11 | 60 ± 9 |
| Systolic BP at rest | 135 ± 17 | 134 ± 16 | 126 ± 21 | 108 ± 8 |
| Mean arterial BP at rest | 91 ± 11 | 92 ± 21 | 84 ± 14 | 80 ± 13 |
| RPP at rest | 8,682 ± 1,368 | 8,717 ± 1,575 | 8,100 ± 2,423 | 6,588 ± 1,056 |
| Peak HR | 80 ± 14 | 83 ± 11 | 82 ± 16 | 87 ± 24 |
| Peak systolic BP | 139 ± 23 | 127 ± 20 | 124 ± 19 | 110 ± 16 |
| Peak mean arterial BP | 93 ± 15 | 84 ± 16 | 81 ± 13 | 73 ± 31 |
| Peak RPP | 11,053 ± 2,657 | 10,414 ± 2,137 | 10,165 ± 2,373 | 9,586 ± 2,976 |
| Coronary hemodynamics | ||||
| MBF at rest | 1.13 ± 0.19 | 1.09 ± 0.18 | 0.83 ± 0.15 | 0.61 ± 0.14 |
| MBF at rest, corrected | 1.18 ± 0.32 | 1.15 ± 0.27 | 0.91 ± 0.23 | 0.79 ± 0.22 |
| Peak MBF during stress | 2.81 ± 1.02 | 2.71 ± 1.11 | 1.72 ± 0.41 | 1.92 ± 0.28 |
| CFR | 2.51 ± 0.89 | 2.40 ± 0.96 | 2.00 ± 0.67 | 2.58 ± 0.68 |
| CVR at rest | 84.8 ± 23.5 | 85.1 ± 28.8 | 103.2 ± 44.7 | 102.1 ± 34.1 |
| Peak CVR during stress | 37.8 ± 16.0 | 36.9 ± 17.45 | 51.4 ± 19.6 | 41.9 ± 4.2 |
HR = heart rate, in bpm; BP = blood pressure, in mm Hg; CVR = coronary vascular resistance, which is calculated as mean arterial BP/MBF and reported in mm Hg/mL/g/min.
RPP is calculated as heart rate (in bpm) × systolic blood pressure (in mm Hg). MBF is reported in mL/g/min. CFR is calculated as peak MBF during stress/MBF at rest.