TABLE 1

Biodistribution of ⁶⁴Cu Activity in HNSCC Tumor Models

	⁶⁴Cu-DOTA-panitumumab (%ID/g)				⁶⁴Cu-DOTA-IgG (%ID/g)
Site	4 h	20 h	30 h	48 h	4 h	20 h	30 h	48 h
Blood	22.73 ± 3.99	14.42 ± 4.47	12.35 ± 4.25	10.29 ± 4.04	20.54 ± 2.58	13.84 ± 2.24	13.01 ± 1.28	11.49 ± 1.99
Liver	15.94 ± 3.35	12.52 ± 3.29	11.96 ± 3.87	11.55 ± 3.64	13.77 ± 2.04	10.42 ± 1.17	10.92 ± 1.77	10.83 ± 2.25
Muscle	3.32 ± 1.50	2.479 ± 1.08	2.79 ± 1.31	2.14 ± 1.03	2.63 ± 0.78	2.20 ± 0.40	2.72 ± 0.83	2.10 ± 0.11
22B	16.09 ± 6.52	26.41 ± 9.16	31.42 ± 10.77	34.80 ± 9.26	5.70 ± 3.92	10.27 ± 5.27	11.75 ± 6.35	12.14 ± 6.71
SAS	6.39 ± 1.60^*	11.01 ± 1.84^*	12.39 ± 4.15^*	15.35 ± 3.33^*	3.51 ± 0.86	6.26 ± 0.68	7.20 ± 2.25	8.05 ± 3.75
SQB20	4.02 ± 1.87^†	7.92 ± 1.48^†	8.76 ± 1.07^†	9.39 ± 1.44^†	3.54 ± 1.04	5.07 ± 2.30	7.26 ± 5.15	8.57 ± 5.04

↵* P < 0.05.
↵† P < 0.01.
22B = UM-SCC-22B.
Data are %ID/g and represent mean ± SD of 4 mice.