Biodistribution of 125I-IPOS in FM3A-Implanted Mice
| Time after injection (h) | ||||
|---|---|---|---|---|
| Organ | 1 | 6 | 24 | 48 |
| Blood | 15.55 ± 1.06 | 3.14 ± 0.54 | 0.18 ± 0.12 | 0.01 ± 0.01 |
| Liver | 32.97 ± 1.03 | 13.80 ± 0.87 | 0.97 ± 0.44 | 0.30 ± 0.06 |
| Spleen | 17.29 ± 2.35 | 6.07 ± 0.73 | 1.21 ± 0.53 | 0.19 ± 0.05 |
| Kidney | 5.51 ± 0.36 | 2.79 ± 0.47 | 0.74 ± 0.60 | 0.09 ± 0.02 |
| Stomach | 2.25 ± 0.57 | 0.62 ± 0.32 | 0.49 ± 0.31 | 0.04 ± 0.02 |
| Neck | 2.39 ± 0.06 | 0.80 ± 0.08 | 0.09 ± 0.04 | 0.00 ± 0.01 |
| Intestine | 7.96 ± 0.09 | 9.82 ± 1.61 | 0.91 ± 0.13 | 0.24 ± 0.08 |
| Tumor | 1.47 ± 1.02 | 1.49 ± 0.38 | 0.28 ± 0.08 | 0.07 ± 0.05 |
| Muscle | 0.94 ± 0.65 | 0.28 ± 0.05 | 0.07 ± 0.06 | 0.00 ± 0.01 |
| Tumor/blood | 0.10 ± 0.07 | 0.49 ± 0.18 | 1.79 ± 0.59 | 6.72 ± 6.61 |
Organ uptake values are expressed as %ID/g of tissue except for tumor/blood. Values are mean ± SD; n = 3–5.