TABLE 2

Results for the 46 Patients

ParameterResult
Mean injected dose (MBq)219 (median, 219; range, 147–286)
Total number of sentinel nodes visualized with planar imaging102 (and 8 uncertain sentinel nodes, probably second-echelon)
 Sentinel nodes detected on early images: 37%
 Additional sentinel nodes visible on late images: 63%
Total number of sentinel nodes visualized with SPECT/CT196 (and 1 uncertain sentinel node, probably second-echelon)
Number of patients with additional sentinel nodes localized by SPECT/CT29 (63%)
Importance of SPECT/CTNo advantage: 6 (13%)
Presumable advantage: 11 (24%)
Definite advantage: 29 (63%)
Patients with uncommonly located sentinel nodes (outside pelvic area)16 (35% of all patients):
 Visible on planar imaging: 7 (44%)
 Detected by SPECT/CT only: 9 (56%)
Node-positive patients15 (33%)
 Metastasis in only sentinel nodes seen on planar images: 8 (53%)
 Metastasis in sentinel nodes exclusively detected by SPECT/CT: 7 (47%)
 Only positive sentinel nodes: 4 (27%)*
  • * In 4 of 7 patients with sentinel node metastasis in sentinel nodes that were exclusively seen on SPECT/CT, this sentinel node was the only positive sentinel node. Those patients (27% of all node-positive patients) were upstaged, and adjuvant therapy was given.