Pharmacokinetic parameter | HRRT reconstruction method | Unfixed intercept | Fixed intercept to origin | |||
---|---|---|---|---|---|---|
Slope | Intercept | r | Slope | r | ||
RLogan DVR | 3D-FBP | 0.99 ± 0.18 | 0.17 ± 0.40 | 0.97 ± 0.01 | 1.03 ± 0.12 | 0.93 ± 0.02 |
3D-FBP G6 | 0.91 ± 0.13 | 0.18 ± 0.32 | 0.98 ± 0.01 | 0.94 ± 0.10 | 0.95 ± 0.01 | |
3D-OSWLS | 1.03 ± 0.17 | 0.00 ± 0.34 | 0.98 ± 0.00 | 1.04 ± 0.13 | 0.96 ± 0.01 | |
3D-OSWLS G6 | 0.89 ± 0.12 | 0.12 ± 0.24 | 0.98 ± 0.00 | 0.92 ± 0.10 | 0.96 ± 0.01 | |
RPM BPND | 3D-FBP | 0.99 ± 0.17 | 0.22 ± 0.20 | 0.97 ± 0.01 | 1.04 ± 0.14 | 0.94 ± 0.03 |
3D-FBP G6 | 0.86 ± 0.18 | 0.27 ± 0.42 | 0.97 ± 0.03 | 0.92 ± 0.11 | 0.91 ± 0.10 | |
3D-OSWLS | 1.05 ± 0.21 | −0.05 ± 0.57 | 0.98 ± 0.01 | 1.04 ± 0.15 | 0.95 ± 0.02 | |
3D-OSWLS G6 | 0.89 ± 0.12 | 0.00 ± 0.36 | 0.98 ± 0.00 | 0.90 ± 0.10 | 0.96 ± 0.01 |
G6 = 6-mm FWHM gaussian kernel.
Slope, intercept, and r (all data are mean ± SD) of reference tissue (pons) kinetic data using HRRT- vs. HR+-reconstructed scans of 4 subjects for 3D-FBP and 5 subjects for 3D-OSWLS, over various ROIs.