Pharmacokinetic parameter | HRRT reconstruction method | Unfixed intercept | Fixed intercept to origin | |||
---|---|---|---|---|---|---|
Slope | Intercept | r | Slope | r | ||
RLogan DVR | 3D-FBP | 0.74 ± 0.25 | 0.94 ± 0.40 | 0.94 ± 0.02 | 0.93 ± 0.27 | 0.88 ± 0.11 |
3D-FBP G6 | 0.97 ± 0.41 | 0.10 ± 0.46 | 0.98 ± 0.00 | 0.99 ± 0.34 | 0.98 ± 0.01 | |
3D-OSWLS | 1.04 ± 0.07 | 0.17 ± 0.38 | 0.97 ± 0.01 | 1.07 ± 0.11 | 0.97 ± 0.01 | |
3D-OSWLS G6 | 0.87 ± 0.18 | 0.18 ± 0.27 | 0.98 ± 0.00 | 0.91 ± 0.16 | 0.98 ± 0.00 | |
RPM BPND | 3D-FBP | 0.89 ± 0.35 | 0.94 ± 0.44 | 0.97 ± 0.01 | 1.10 ± 0.43 | 0.92 ± 0.07 |
3D-FBP G6 | 0.97 ± 0.38 | 0.10 ± 0.26 | 0.98 ± 0.00 | 1.00 ± 0.40 | 0.98 ± 0.01 | |
3D-OSWLS | 1.10 ± 0.12 | 0.29 ± 0.41 | 0.97 ± 0.01 | 1.16 ± 0.14 | 0.97 ± 0.01 | |
3D-OSWLS G6 | 0.91 ± 0.23 | 0.02 ± 0.22 | 0.98 ± 0.00 | 0.91 ± 0.20 | 0.98 ± 0.00 |
G6 = 6-mm FWHM gaussian kernel.
Slope, intercept, and r (all data are mean ± SD) of reference tissue (pons) kinetic data using HRRT- vs. HR+-reconstructed scans of 6 subjects, over various ROIs.