Plasma Input Parametric Image Data
| Pharmacokinetic parameter | HRRT reconstruction method | Unfixed intercept | Fixed intercept to origin | |||
|---|---|---|---|---|---|---|
| Slope | Intercept | r | Slope | r | ||
| Logan VT | 3D-FBP | 0.83 ± 0.13 | 0.78 ± 0.54 | 0.94 ± 0.03 | 0.99 ± 0.12 | 0.91 ± 0.08 |
| 3D-FBP G6 | 1.03 ± 0.05 | 0.21 ± 0.40 | 0.98 ± 0.00 | 1.07 ± 0.11 | 0.98 ± 0.01 | |
| 3D-OSWLS | 1.04 ± 0.07 | 0.17 ± 0.38 | 0.97 ± 0.01 | 1.07 ± 0.11 | 0.97 ± 0.01 | |
| 3D-OSWLS G6 | 0.98 ± 0.06 | 0.15 ± 0.30 | 0.99 ± 0.00 | 1.01 ± 0.10 | 0.98 ± 0.00 | |
| BFM VT | 3D-FBP | 1.00 ± 0.14 | 1.44 ± 0.80 | 0.96 ± 0.01 | 1.29 ± 0.20 | 0.89 ± 0.12 |
| 3D-FBP G6 | 1.05 ± 0.11 | 0.18 ± 0.41 | 0.98 ± 0.01 | 1.09 ± 0.15 | 0.98 ± 0.01 | |
| 3D-OSWLS | 1.10 ± 0.12 | 0.29 ± 0.41 | 0.97 ± 0.01 | 1.16 ± 0.14 | 0.97 ± 0.01 | |
| 3D-OSWLS G6 | 0.98 ± 0.06 | 0.11 ± 0.32 | 0.98 ± 0.00 | 1.00 ± 0.10 | 0.98 ± 0.00 | |
G6 = 6-mm FWHM gaussian kernel.
Slope, intercept, and r (all data are mean ± SD) of plasma input kinetic data using HRRT- vs. HR+-reconstructed scans of 5 subjects, over various ROIs.