Baseline Characteristics of Clinical Responders and Nonresponders
| Baseline characteristic | Responders (n = 24) | Nonresponders (n = 16) | P |
|---|---|---|---|
| Age (y) | 62 ± 8 | 64 ± 9 | NS |
| M/F | 20/4 | 12/4 | NS |
| Ischemic etiology | 16 (67) | 12 (75) | NS |
| Clinical evaluation | |||
| NYHA class | 3.0 ± 0.2 | 3.2 ± 0.5 | NS |
| QoL score | 34 ± 17 | 45 ± 20 | NS |
| 6-MWT (m) | 354 ± 81 | 272 ± 99 | 0.01 |
| QRS (ms) | 162 ± 35 | 146 ± 31 | NS |
| 2D echocardiographic parameters | |||
| LVEDV (mL) | 274 ± 79 | 219 ± 83 | 0.04 |
| LVESV (mL) | 211 ± 75 | 167 ± 78 | NS |
| LVEF (%) | 24 ± 8 | 25 ± 8 | NS |
| LV dyssynchrony (ms) | 62 ± 37 | 40 ± 26 | 0.04 |
| Phase distribution | |||
| Bandwidth (°) | 94 ± 23 | 68 ± 21 | <0.01 |
| Phase SD (°) | 26 ± 6 | 18 ± 5 | <0.01 |
| Cardiac segments with perfusion defect | 5 ± 2 | 8 ± 2 | <0.01 |
Data are represented as mean ± SD or number, with percentages in parentheses.
NS = not significant; NYHA = New York Heart Association; QoL = quality of life; 6-MWT = 6-min walk test; 2D = 2-dimensional; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; LVEF = left ventricular ejection fraction; SD = standard deviation.